Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5320324 | 1.00 | HPGD (0.54) | HPGDTAS1R3TAS1R1ALDH1A1LMNA | |
| SCHEMBL5323145 | 0.84 | TAS1R3 (0.51) | TAS1R3TAS1R1LMNAHTTSMN1; SMN2 | |
| SCHEMBL5323140 | 0.84 | TAS1R3 (0.51) | TAS1R3TAS1R1LMNAHTTSMN1; SMN2 | |
| SCHEMBL701392 | 0.80 | TAS1R3 (0.76) | TAS1R3TAS1R1 | |
| SCHEMBL701391 | 0.80 | TAS1R3 (0.76) | TAS1R3TAS1R1 | |
| SCHEMBL27388963 | 0.79 | TAS1R3 (0.54) | HPGDTAS1R3TAS1R1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4413482 | 0.77 | SMN1; SMN2 (0.53) | HPGDLMNATDP1HTTSMN1; SMN2 | |
| SCHEMBL4413478 | 0.77 | SMN1; SMN2 (0.53) | HPGDLMNATDP1HTTSMN1; SMN2 | |
| SCHEMBL27497674 | 0.76 | ALDH1A1 (0.63) | HPGDALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL1824758 | 0.76 | NOS3 (0.57) | TAS1R3TAS1R1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848289-A2 | AROMATIC AMIDES AND UREAS AND THEIR USES AS SWEET AND/OR UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS | Senomyx, Inc. (US) | 2007-10-31 | — | — | EP | disclosed |
| WO-2006084246-A2 | AROMATIC AMIDES AND UREAS AND THEIR USES AS SWEET AND/OR UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS | SENOMYX, INC. (US) | 2006-08-10 | — | — | WO | disclosed |