Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | PARP10 | Q53GL7 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL999801 | 0.89 | TSHR (0.54) | PARP1TSHRHSD17B10TDP1MAPT | |
| Benzene SCHEMBL27546891 | 0.83 | KMT2A (0.39) | TSHRHSD17B10TDP1MAPTCYP2C19 | |
| Toluene SCHEMBL26697033 | 0.82 | TSHR (0.44) | PARP1TSHRHSD17B10TDP1MAPT | |
| Aniline SCHEMBL27495165 | 0.82 | TSHR (0.44) | PARP1TSHRHSD17B10TDP1MAPT | |
| Benzamide SCHEMBL28302953 | 0.82 | TSHR (0.53) | PARP1TSHRHSD17B10TDP1MAPT | |
| Aniline SCHEMBL28104783 | 0.81 | KMT2A (0.42) | PARP1TSHRHSD17B10TDP1MAPT | |
| Chlorobenzene SCHEMBL27484099 | 0.81 | KMT2A (0.42) | PARP1TSHRHSD17B10TDP1MAPT | |
| Fluorobenzene SCHEMBL27926129 | 0.81 | KCNN4 (0.46) | PARP1TSHRHSD17B10TDP1MAPT | |
| Benzamide SCHEMBL29825021 | 0.79 | PARP1 (0.73) | PARP1TSHRHSD17B10TDP1MAPT | |
| Benzamide SCHEMBL2061911 | 0.79 | PARP1 (0.89) | PARP1TSHRHSD17B10TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101203499-A | Alkyl sulfonamide derivatives | LUNDBECK AS CO H (DK) | 2008-06-18 | — | — | CN | disclosed |
| WO-2007103295-A2 | HALOGENATED SULFONAMIDE DERIVATIVES | H. LUNDBECK A/S (DK) | 2007-09-13 | — | — | WO | disclosed |
| US-20070213376-A1 | Halogenated sulfonamide derivatives | H. LUNDBECK A/S (DK) | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213376-A1 | Halogenated sulfonamide derivatives | NPY5R, NPY2R, SSTR5 | PARP1 4712/4885TSHR 37/4885HSD17B10 1502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.