Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5321360 | 0.83 | MEN1 (0.57) | L3MBTL1RAB9AIDO1MAPTNPC1 | |
| SCHEMBL5321338 | 0.83 | CXCR2 (0.47) | L3MBTL1RAB9AIDO1MAPTNPC1 | |
| SCHEMBL5648662 | 0.83 | L3MBTL1 (0.48) | L3MBTL1RAB9AMAPTNPC1MEN1 | |
| SCHEMBL5318232 | 0.83 | RAB9A (0.47) | L3MBTL1RAB9AMAPTNPC1MEN1 | |
| SCHEMBL5321466 | 0.80 | MAPT (0.60) | L3MBTL1IDO1MAPTSCN9AALDH1A1 | |
| SCHEMBL5649167 | 0.76 | CXCR2 (0.51) | L3MBTL1IDO1MAPTMEN1KMT2A | |
| SCHEMBL5321476 | 0.76 | DAO (0.40) | L3MBTL1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL11973215 | 0.76 | L3MBTL1 (0.48) | L3MBTL1RAB9AMAPTNPC1MEN1 | |
| SCHEMBL30553438 | 0.76 | L3MBTL1 (0.48) | L3MBTL1RAB9AMAPTNPC1MEN1 | |
| SCHEMBL1492564 | 0.74 | PIK3CD (0.47) | RAB9AMAPTNPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007091140-A1 | SUBSTITUTED PHENYLSULFAMOYL COMPOUNDS AS PPAR AGONISTS | PFIZER PRODUCTS INC. (US) | 2007-08-16 | — | — | WO | disclosed |