Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.40 |
| ▸ | GPR183 | P32249 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | ESRRG | P62508 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5321466 | 0.85 | MAPT (0.60) | SCN9AMAPTDAOALDH1A1L3MBTL1 | |
| SCHEMBL5320880 | 0.83 | L3MBTL1 (0.51) | RAB9AKDM4EPOLBSCN9AMAPT | |
| SCHEMBL5321360 | 0.80 | MEN1 (0.57) | RAB9AMAPTLMNASMN1; SMN2DAO | |
| SCHEMBL5321338 | 0.80 | CXCR2 (0.47) | RAB9AKDM4EPOLBMAPTSMN1; SMN2 | |
| SCHEMBL5648662 | 0.79 | L3MBTL1 (0.48) | RAB9APOLBMAPTSMN1; SMN2NPC1 | |
| SCHEMBL5654702 | 0.79 | MAPT (0.56) | RAB9AKDM4ESCN9AMAPTALDH1A1 | |
| SCHEMBL5320690 | 0.77 | MAPT (0.60) | RAB9AKDM4EPOLBMAPTLMNA | |
| SCHEMBL11714659 | 0.76 | RAB9A (0.50) | RAB9AKDM4EPOLBMAPTNPC1 | |
| SCHEMBL5368718 | 0.76 | ALDH1A1 (0.61) | RAB9ASCN9ASCN5AGRIN2CMAPT | |
| SCHEMBL5649167 | 0.73 | CXCR2 (0.51) | MAPTLMNASMN1; SMN2DAOMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007091140-A1 | SUBSTITUTED PHENYLSULFAMOYL COMPOUNDS AS PPAR AGONISTS | PFIZER PRODUCTS INC. (US) | 2007-08-16 | — | — | WO | disclosed |