Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.58 |
| ▸ | JAK2 | O60674 | 1/20 | 0.58 |
| ▸ | ABL1 | P00519 | 1/20 | 0.58 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.58 |
| ▸ | LCK | P06239 | 1/20 | 0.58 |
| ▸ | FYN | P06241 | 1/20 | 0.58 |
| ▸ | CSF1R | P07333 | 1/20 | 0.58 |
| ▸ | RET | P07949 | 1/20 | 0.58 |
| ▸ | IGF1R | P08069 | 1/20 | 0.58 |
| ▸ | MET | P08581 | 1/20 | 0.58 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.58 |
| ▸ | PIM1 | P11309 | 1/20 | 0.58 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.58 |
| ▸ | PRKACA | P17612 | 1/20 | 0.58 |
| ▸ | KDR | P35968 | 1/20 | 0.58 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.58 |
| ▸ | CDK8 | P49336 | 1/20 | 0.58 |
| ▸ | GSK3A | P49840 | 1/20 | 0.58 |
| ▸ | GSK3B | P49841 | 1/20 | 0.58 |
| ▸ | CDK7 | P50613 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Silver SCHEMBL5832836 | 0.96 | AURKA (0.58) | AURKAJAK2ABL1NTRK1LCK | |
| Zinc Ion SCHEMBL5318534 | 0.96 | AURKA (0.58) | AURKAJAK2ABL1NTRK1LCK | |
| Lithium Ion SCHEMBL15813273 | 0.96 | AURKA (0.58) | AURKAJAK2ABL1NTRK1LCK | |
| Phosphine SCHEMBL25354668 | 0.95 | AURKA (0.56) | AURKAJAK2ABL1NTRK1LCK | |
| SCHEMBL250171 | 0.82 | CCND3 (0.70) | AURKAJAK2ABL1NTRK1LCK | |
| SCHEMBL6563583 | 0.81 | ALDH1A1 (0.53) | AURKAJAK2ABL1NTRK1LCK | |
| SCHEMBL160155 | 0.81 | AURKA (0.61) | AURKAJAK2ABL1NTRK1LCK | |
| SCHEMBL29414293 | 0.81 | AURKA (0.61) | AURKAJAK2ABL1NTRK1LCK | |
| SCHEMBL5358948 | 0.81 | AURKA (0.61) | AURKAJAK2ABL1NTRK1LCK | |
| Hydrochloric Acid SCHEMBL7000982 | 0.81 | CCND3 (0.68) | AURKAJAK2ABL1NTRK1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007087434-A2 | METHOD FOR THE PRODUCTION OF COPPER AND ZINC MONO-AND BI-METALLIC IMIDAZOLATES | U.S. BORAX INC. (US) | 2007-08-02 | — | — | WO | disclosed |