SCHEMBL5358948

SCHEMBL5358948

[O]C(=O)c1nc2ccccc2[nH]1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AURKA O14965 1/20 0.61
JAK2 O60674 1/20 0.61
ABL1 P00519 1/20 0.61
NTRK1 P04629 1/20 0.61
LCK P06239 1/20 0.61
FYN P06241 1/20 0.61
CSF1R P07333 1/20 0.61
RET P07949 1/20 0.61
IGF1R P08069 1/20 0.61
MET P08581 1/20 0.61
PDGFRB P09619 1/20 0.61
PIM1 P11309 1/20 0.61
FGFR1 P11362 1/20 0.61
PRKACA P17612 1/20 0.61
KDR P35968 1/20 0.61
MAP2K2 P36507 1/20 0.61
CDK8 P49336 1/20 0.61
GSK3A P49840 1/20 0.61
GSK3B P49841 1/20 0.61
CDK7 P50613 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL250171 0.86 CCND3 (0.70) AURKAJAK2ABL1NTRK1LCK
SCHEMBL160155 0.84 AURKA (0.61) AURKAJAK2ABL1NTRK1LCK
Hydrochloric Acid SCHEMBL7000982 0.84 CCND3 (0.68) AURKAJAK2ABL1NTRK1LCK
SCHEMBL29414293 0.84 AURKA (0.61) AURKAJAK2ABL1NTRK1LCK
SCHEMBL4770509 0.82 AURKA (0.59) AURKAJAK2ABL1NTRK1LCK
Hydrochloric Acid SCHEMBL3808279 0.82 AURKA (0.59) AURKAJAK2ABL1NTRK1LCK
SCHEMBL3808272 0.82 AURKA (0.59) AURKAJAK2ABL1NTRK1LCK
Water SCHEMBL16239370 0.82 AURKA (0.59) AURKAJAK2ABL1NTRK1LCK
SCHEMBL1132610 0.82 MAPT (0.62) AURKAJAK2ABL1NTRK1LCK
SCHEMBL828618 0.82 AURKA (0.59) AURKAJAK2ABL1NTRK1LCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4371979-A1 FORMAMIDE DERIVATIVE AND AGRICULTURAL OR HORTICULTURAL PLANT DISEASE CONTROL AGENT Kumiai Chemical Industry Co., Ltd. (JP) 2024-05-22 EP disclosed
WO-2024057812-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL CURED LAYER, OPTICAL FILM, POLARIZING PLATE, IMAGE DISPLAY DEVICE, MONOMER, AND COPOLYMER 富士フイルム株式会社 2024-03-21 WO disclosed
CN-117693500-A Carboxamide derivative and agricultural/horticultural plant disease control agent 组合化学工业株式会社 2024-03-12 CN disclosed
US-11914248-B2 Photo-alignment copolymer, photo-alignment film, and optical laminate FUJIFILM CORPORATION (JP) 2024-02-27 US disclosed
US-11827727-B2 Photo-alignment polymer, binder composition, binder layer, optical laminate, optical laminate manufacturing method, and image display device FUJIFILM CORPORATION (JP) 2023-11-28 US disclosed
US-20230305209-A1 OPTICAL LAMINATE, POLARIZING PLATE, AND IMAGE DEVICE DISPLAY FUJIFILM CORPORATION (JP) 2023-09-28 US disclosed
US-20230167216-A1 PHOTO-ALIGNMENT POLYMER, BINDER COMPOSITION, BINDER LAYER, OPTICAL LAMINATE, OPTICAL LAMINATE MANUFACTURING METHOD, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-06-01 US disclosed
US-20230138456-A1 BINDER COMPOSITION, COMPOUND, BINDER LAYER, OPTICAL LAMINATE, OPTICAL LAMINATE MANUFACTURING METHOD, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-05-04 US disclosed
US-20230088847-A1 OPTICAL LAMINATE, POLARIZING PLATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-03-23 US disclosed
WO-2023286855-A1 FORMAMIDE DERIVATIVE AND AGRICULTURAL OR HORTICULTURAL PLANT DISEASE CONTROL AGENT クミアイ化学工業株式会社 2023-01-19 WO disclosed
US-20170117100-A1 PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, METAL COMPLEX DYE, DYE SOLUTION, AND TERPYRIDINE COMPOUND OR ESTERIFIED PRODUCT THEREOF FUJIFILM CORPORATION (JP) 2017-04-27 US disclosed
EP-3157028-A1 PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, METAL-COMPLEX PIGMENT, AND PIGMENT SOLUTION Fujifilm Corporation (JP) 2017-04-19 EP disclosed
EP-3157026-A1 PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, METAL-COMPLEX PIGMENT, PIGMENT SOLUTION, AND TERPYRIDINE COMPOUND OR ESTERIFIED TERPYRIDINE COMPOUND Fujifilm Corporation (JP) 2017-04-19 EP disclosed
US-20170092435-A1 PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, METAL COMPLEX DYE, DYE SOLUTION, AND TERPYRIDINE COMPOUND OR ESTERIFIED PRODUCT THEREOF FUJIFILM CORPORATION (JP) 2017-03-30 US disclosed
US-20170092434-A1 PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, METAL COMPLEX DYE, AND DYE SOLUTION FUJIFILM CORPORATION (JP) 2017-03-30 US disclosed
US-9564274-B2 Metal complex dye, photoelectric conversion element, dye-sensitized solar cell, dye solution, and compound FUJIFILM CORPORATION (JP) 2017-02-07 US disclosed
EP-2793311-A1 METAL COMPLEX DYE, PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, DYE SOLUTION, AND COMPOUND Fujifilm Corporation (JP) 2014-10-22 EP disclosed
US-20140290746-A1 METAL COMPLEX DYE, PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, DYE SOLUTION, AND COMPOUND FUJIFILM CORPORATION (JP) 2014-10-02 US disclosed
US-7217723-B2 Substituted benzothiophenes, e.g., 7Z)-7-hydroxyimino-4,5,6,7-tetrahydro-benzo[b]thiophene-3-sulfonic acid [2-(4-fluorophenyl)-2-hydroxyethyl]-methyl-amide; treating allergies such as atopic dermatitis, allergic coryza, bronchial asthma, hypersensitive pneumoniac and pulmonary aspergillosis. EISAI CO., LTD. (JP) 2007-05-15 US disclosed
US-20050227959-A1 Heterocyclic compound having oxime group EISAI CO., LTD. (JP) 2005-10-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170092435-A1 PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, METAL COMPLEX DYE, DYE SOLUTION, AND TERPYRIDINE COMPOUND OR ESTERIFIED PRODUCT THEREOF CRY2, CACNA1S, CACNA1E AURKA 4692/4885JAK2 2595/4885ABL1 1890/4885
US-20170117100-A1 PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, METAL COMPLEX DYE, DYE SOLUTION, AND TERPYRIDINE COMPOUND OR ESTERIFIED PRODUCT THEREOF DLK1, CACNA1C, CRY1 AURKA 3691/4885JAK2 2543/4885ABL1 1770/4885
US-20050227959-A1 Heterocyclic compound having oxime group STAT6, HRH4, HRH2 AURKA 2780/4885JAK2 7/4885ABL1 222/4885
US-20170092434-A1 PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, METAL COMPLEX DYE, AND DYE SOLUTION CRY2, CRY1, MYL4 AURKA 3873/4885JAK2 2607/4885ABL1 2760/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.