Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 13/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PNKP | Q96T60 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5287349 | 0.86 | PTH1R (0.44) | PTH1RMAPTMAPK1ALDH1A1HTT | |
| SCHEMBL5325257 | 0.85 | PTH1R (0.44) | PTH1R | |
| SCHEMBL5321708 | 0.82 | PTH1R (0.56) | PTH1RALDH1A1 | |
| SCHEMBL5327453 | 0.75 | PTH1R (0.45) | PTH1RMAPTMEN1GAAKMT2A | |
| SCHEMBL5319870 | 0.75 | PTH1R (0.60) | PTH1RMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5320431 | 0.74 | PTH1R (0.48) | PTH1R | |
| SCHEMBL5328340 | 0.73 | PTH1R (0.50) | PTH1RMAPTMEN1GAAKMT2A | |
| SCHEMBL5329914 | 0.73 | PTH1R (0.47) | PTH1RMAPTSCN2AACHEHTT | |
| SCHEMBL5324664 | 0.72 | PTH1R (0.58) | PTH1RACHE | |
| SCHEMBL5322971 | 0.71 | PTH1R (0.54) | PTH1RMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006129120-A9 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-03-22 | — | — | WO | disclosed |
| WO-2006129120-A2 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2006-12-07 | — | — | WO | disclosed |