Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14691647 | 0.78 | NPSR1 (0.44) | NPSR1CYP2C9KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL27500132 | 0.75 | KMT2A (0.44) | NPSR1CYP2C9KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL625122 | 0.75 | KMT2A (0.44) | NPSR1CYP2C9KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL27224598 | 0.72 | CYP1A2 (0.45) | NPSR1CYP2C9KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL5347581 | 0.72 | NPSR1 (0.39) | NPSR1CYP2C9KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL421668 | 0.72 | NPSR1 (0.39) | NPSR1CYP2C9KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL6180241 | 0.72 | NPSR1 (0.39) | NPSR1CYP2C9KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL5669770 | 0.71 | ALDH1A1 (0.44) | NPSR1CYP2C9KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL5669762 | 0.71 | ALDH1A1 (0.44) | NPSR1CYP2C9KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL6834107 | 0.69 | SMN1; SMN2 (0.47) | NPSR1CYP2C9KMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070258899-A1 | Diagnostic and therapeutic agents | KARYON-CTT LTD (FI) | 2007-11-08 | — | — | US | disclosed |
| WO-2007113385-A1 | DIAGNOSTIC AND THERAPEUTIC AGENTS | KARYON-CTT LTD (FI) | 2007-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070258899-A1 | Diagnostic and therapeutic agents | YBX1, MLX, TPX2 | NPSR1 3367/4885CYP2C9 4588/4885KMT2A 3586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.