Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 7/20 | 0.50 |
| ▸ | AKT2 | P31751 | 7/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5344323 | 0.88 | CYP3A4 (0.44) | AKT1AKT2CYP2A6SLC2A1RAB9A | |
| SCHEMBL5324372 | 0.87 | AKT1 (0.55) | AKT1AKT2RAB9AKDM4EALDH1A1 | |
| SCHEMBL5325683 | 0.84 | AKT1 (0.51) | AKT1AKT2RAB9AKDM4EALDH1A1 | |
| SCHEMBL5341386 | 0.81 | AKT1 (0.49) | AKT1AKT2SLC2A1RAB9AKDM4E | |
| SCHEMBL5321323 | 0.81 | AKT1 (0.50) | AKT1AKT2SLC2A1RAB9AKDM4E | |
| SCHEMBL5322231 | 0.81 | AKT1 (0.48) | AKT1AKT2RAB9AKDM4EALDH1A1 | |
| SCHEMBL5349048 | 0.81 | AKT1 (0.48) | AKT1AKT2RAB9AKDM4EALDH1A1 | |
| SCHEMBL5320129 | 0.79 | AKT1 (0.46) | AKT1AKT2SLC2A1RAB9AKDM4E | |
| SCHEMBL5343647 | 0.79 | AKT1 (0.48) | AKT1AKT2RAB9AKDM4EALDH1A1 | |
| SCHEMBL5338540 | 0.78 | AKT1 (0.46) | AKT1AKT2RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096764-A2 | BICYCLIC HETEROARYL DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-08-30 | — | — | WO | claimed |
| WO-2007096764-A2 | BICYCLIC HETEROARYL DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-08-30 | — | — | WO | disclosed |