Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.46 |
| ▸ | AKT2 | P31751 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5344599 | 0.99 | AKT1 (0.45) | AKT1AKT2MAOBADORA2AADORA1 | |
| SCHEMBL5346776 | 0.95 | AKT1 (0.42) | AKT1AKT2MAOBADORA2AADORA1 | |
| SCHEMBL5319387 | 0.92 | AKT1 (0.41) | AKT1AKT2MAOBADORA2AADORA1 | |
| SCHEMBL5343644 | 0.92 | GRIN1 (0.46) | AKT1AKT2RAB9ATDP1NPC1 | |
| SCHEMBL5343214 | 0.90 | TDP1 (0.47) | AKT1AKT2MAOBADORA2AADORA1 | |
| SCHEMBL5340690 | 0.88 | MAOB (0.40) | MAOBADORA2AADORA1RAB9ATDP1 | |
| SCHEMBL5324596 | 0.88 | TDP1 (0.46) | AKT1AKT2MAOBADORA2AADORA1 | |
| SCHEMBL5341386 | 0.86 | AKT1 (0.49) | AKT1AKT2RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL5325683 | 0.86 | AKT1 (0.51) | AKT1AKT2ADORA2AADORA1RAB9A | |
| SCHEMBL5344366 | 0.85 | TDP1 (0.43) | AKT1AKT2MAOBADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096764-A2 | BICYCLIC HETEROARYL DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-08-30 | — | — | WO | claimed |
| WO-2007096764-A2 | BICYCLIC HETEROARYL DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-08-30 | — | — | WO | disclosed |