Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16175447 | 0.74 | CHRNB2 (0.36) | F2F10PRSS1 | |
| Hydrochloric Acid SCHEMBL7509696 | 0.69 | TBXA2R (0.42) | MEN1GAAKMT2ASMN1; SMN2F2 | |
| SCHEMBL5178587 | 0.69 | CHRNB2 (0.37) | MEN1GAAKMT2ASMN1; SMN2F2 | |
| SCHEMBL6601842 | 0.68 | EGFR (0.36) | MEN1KMT2AALDH1A1 | |
| SCHEMBL21808887 | 0.68 | KMT2A (0.43) | MEN1GAAKMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL21808880 | 0.67 | CYP1A2 (0.46) | MEN1GAAKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL21808886 | 0.67 | MEN1 (0.47) | MEN1GAAKMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL27718829 | 0.67 | LMNA (0.38) | MEN1KMT2AHSD17B10ALDH1A1MAPK1 | |
| SCHEMBL12369307 | 0.66 | CHRNB2 (0.37) | KMT2AF2F10PRSS1 | |
| SCHEMBL21808881 | 0.66 | KMT2A (0.43) | KMT2ASMN1; SMN2OPRM1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007097697-A1 | THERAPEUTIC QUINOLINE COMPOUNDS THAT ARE 5HT1B MODULATORS | ASTRAZENECA AB (SE) | 2007-08-30 | — | — | WO | disclosed |