Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3046228 | 0.88 | CHRNB2 (0.36) | CHRNB2CHRNA4 | |
| SCHEMBL1688323 | 0.77 | CCKBR (0.42) | — | |
| SCHEMBL27799841 | 0.77 | CHRNB4 (0.46) | CHRNB2CHRNA4 | |
| SCHEMBL20308980 | 0.77 | PNMT (0.34) | F2F10PRSS1 | |
| SCHEMBL5322624 | 0.74 | MEN1 (0.34) | F2F10PRSS1 | |
| SCHEMBL7006440 | 0.72 | ESR2 (0.38) | CHRNB2CHRNA4 | |
| SCHEMBL6606248 | 0.69 | DRD4 (0.47) | — | |
| SCHEMBL14209086 | 0.67 | CHRNB2 (0.42) | CHRNB2CHRNA4 | |
| SCHEMBL15331448 | 0.67 | PARP3 (0.47) | — | |
| SCHEMBL15331452 | 0.67 | PARP3 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2668177-B1 | SUBSTITUTED PYRIDINYL-PYRIMIDINES AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INT (DE) | 2014-10-22 | — | — | EP | disclosed |