Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 12/20 | 0.51 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.51 |
| ▸ | PTPRC | P08575 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | CDC14B | O60729 | 1/20 | 0.43 |
| ▸ | CDC14A | Q9UNH5 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5344606 | 0.89 | HDAC1 (0.53) | PTPN1PTPN2PTPRCHDAC6HDAC1 | |
| SCHEMBL5319947 | 0.86 | CA1 (0.56) | PTPN1PTPN2PTPRCHDAC6HDAC1 | |
| SCHEMBL5340406 | 0.85 | CA1 (0.57) | PTPN1PTPN2PTPRCHDAC6HDAC1 | |
| SCHEMBL14467239 | 0.85 | CA1 (0.57) | PTPN1PTPN2PTPRCHDAC6HDAC1 | |
| SCHEMBL5319152 | 0.85 | CA1 (0.57) | PTPN1PTPN2PTPRCHDAC6HDAC1 | |
| SCHEMBL5318338 | 0.81 | PTPN1 (0.48) | PTPN1PTPN2PTPRCALDH1A1KMT2A | |
| SCHEMBL5319160 | 0.81 | PTPN1 (0.46) | PTPN1PTPN2PTPRCHDAC6HDAC1 | |
| SCHEMBL5343124 | 0.80 | PTPN1 (0.47) | PTPN1PTPN2PTPRCCDC14BCDC14A | |
| SCHEMBL5348477 | 0.80 | PTPN1 (0.44) | PTPN1PTPN2PTPRCHDAC6HDAC1 | |
| SCHEMBL5321901 | 0.79 | MAPT (0.44) | PTPN1PTPN2PTPRCHDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007081755-A2 | INDOLE-BENZIMIDAZOLE AND INDAZOLE INHIBITORS OF TYROSINE PHOSPHATASES | METABASIS THERAPEUTICS, INC. (US) | 2007-07-19 | — | — | WO | claimed |