Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 9/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.47 |
| ▸ | PTPRC | P08575 | 2/20 | 0.47 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.42 |
| ▸ | CDC14B | O60729 | 1/20 | 0.41 |
| ▸ | CDC14A | Q9UNH5 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5337560 | 0.84 | HDAC6 (0.55) | PTPN1PTPN2PTPRC | |
| SCHEMBL5319160 | 0.84 | PTPN1 (0.46) | PTPN1PTPN2PTPRCCDC14BCDC14A | |
| SCHEMBL5320081 | 0.80 | PTPN2 (0.45) | PTPN1PTPN2PTPRC | |
| SCHEMBL5322648 | 0.80 | PTPN1 (0.51) | PTPN1PTPN2PTPRCCDC14BCDC14A | |
| SCHEMBL5342941 | 0.77 | PLA2G2A (0.51) | PTPN1PTPN2PTPRC | |
| SCHEMBL5317466 | 0.77 | HDAC1 (0.45) | PTPN1PTPN2PTPRC | |
| SCHEMBL5318293 | 0.77 | IDO1 (0.45) | PTPN1PTPN2PTPRC | |
| SCHEMBL5320802 | 0.77 | HDAC1 (0.44) | PTPN1PTPN2PTPRC | |
| SCHEMBL5320495 | 0.77 | CACNB4 (0.45) | PTPN1PTPN2PTPRC | |
| SCHEMBL5324927 | 0.77 | HDAC1 (0.46) | PTPN1PTPN2PTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007081755-A2 | INDOLE-BENZIMIDAZOLE AND INDAZOLE INHIBITORS OF TYROSINE PHOSPHATASES | METABASIS THERAPEUTICS, INC. (US) | 2007-07-19 | — | — | WO | claimed |