Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 13/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5323601 | 0.91 | CCR2 (0.48) | CCR2DRD2USP2ALDH1A1MAPT | |
| SCHEMBL5323641 | 0.87 | CCR2 (0.47) | CCR2DRD2USP2ALDH1A1MAPT | |
| SCHEMBL5356626 | 0.87 | DRD2 (0.43) | DRD2USP2ALDH1A1MAPTALOX12 | |
| SCHEMBL5324768 | 0.83 | CCR2 (0.49) | CCR2DRD2USP2ALDH1A1MAPT | |
| SCHEMBL5321973 | 0.82 | CCR2 (0.46) | CCR2DRD2USP2ALDH1A1MAPT | |
| SCHEMBL5459675 | 0.81 | CCR2 (0.56) | CCR2ALDH1A1MAPT | |
| SCHEMBL5324932 | 0.81 | CCR2 (0.47) | CCR2DRD2USP2ALDH1A1MAPT | |
| SCHEMBL14387014 | 0.81 | CCR2 (0.56) | CCR2ALDH1A1MAPT | |
| SCHEMBL5354245 | 0.80 | USP2 (0.43) | CCR2DRD2USP2ALDH1A1MAPT | |
| SCHEMBL5327777 | 0.77 | DRD2 (0.45) | DRD2USP2ALDH1A1MAPTALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197590-A1 | SUBSTITUTED DIPIPERIDINE CCR2 ANTAGONISTS | JANSSEN PHARMACEUTCA N.V. (BE) | 2007-08-23 | — | — | US | claimed |
| WO-2007130712-A1 | SUBSTITUTED DIPIPERIDINE AS CCR2 ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | JANSSEN PHARMACEUTICA, NV (BE) | 2007-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197590-A1 | SUBSTITUTED DIPIPERIDINE CCR2 ANTAGONISTS | CCR2, CCR1, CCR5 | CCR2 1/4885DRD2 284/4885USP2 3962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.