Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 7/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.47 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.47 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | HPN | P05981 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL14632606 | 0.82 | F10 (0.50) | F2PRSS1F10 | |
| Hydrochloric Acid SCHEMBL14632425 | 0.82 | F10 (0.50) | F2PRSS1F10 | |
| SCHEMBL4715449 | 0.81 | SMN1; SMN2 (0.44) | CA2 | |
| SCHEMBL14632437 | 0.80 | F10 (0.53) | F2PRSS1F10 | |
| SCHEMBL14632467 | 0.80 | F10 (0.53) | F2PRSS1F10 | |
| SCHEMBL25262222 | 0.80 | TDP1 (0.45) | — | |
| SCHEMBL432319 | 0.79 | SMN1; SMN2 (0.51) | ITGB3 | |
| SCHEMBL15664724 | 0.79 | SMN1; SMN2 (0.51) | ITGB3 | |
| SCHEMBL630857 | 0.79 | SMN1; SMN2 (0.51) | ITGB3 | |
| Hydrochloric Acid SCHEMBL14632408 | 0.79 | F10 (0.52) | F2PRSS1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10100084-B2 | Template-fixed beta-hairpin peptidomimetics with protease inhibitory activity | POLYPHOR LTD. (CH) | 2018-10-16 | — | — | US | disclosed |
| US-20160333051-A1 | TEMPLATE-FIXED BETA-HAIRPIN PEPTIDOMIMETICS WITH PROTEASE INHIBITORY ACTIVITY | POLYPHOR LTD (CH) | 2016-11-17 | — | — | US | disclosed |
| EP-1856140-B1 | TEMPLATE-FIXED BETA-HAIRPIN PEPTIDOMIMETICS WITH PROTEASE INHIBITORY ACTIVITY | POLYPHOR LTD (CH) | 2013-12-25 | — | — | EP | disclosed |
| EP-1856140-A1 | TEMPLATE-FIXED BETA-HAIRPIN PEPTIDOMIMETICS WITH PROTEASE INHIBITORY ACTIVITY | Polyphor Ltd. (CH) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006087001-A1 | TEMPLATE-FIXED BETA-HAIRPIN PEPTIDOMIMETICS WITH PROTEASE INHIBITORY ACTIVITY | POLYPHOR LTD. (CH) | 2006-08-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10100084-B2 | Template-fixed beta-hairpin peptidomimetics with protease inhibitory activity | CTSG, CTRL, PREP | F2 594/4885PRSS1 19/4885PRSS2 16/4885 |
| US-20160333051-A1 | TEMPLATE-FIXED BETA-HAIRPIN PEPTIDOMIMETICS WITH PROTEASE INHIBITORY ACTIVITY | CTSG, CTRL, PREP | F2 594/4885PRSS1 19/4885PRSS2 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.