SCHEMBL14632467

SCHEMBL14632467

N=C(N)c1cccc(N2CCCC[C@@H]2C(=O)O)c1

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
F10 P00742 19/20 0.53
F2 P00734 16/20 0.51
PRSS1 P07477 10/20 0.51
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.43
ALDH1A1 P00352 1/20 0.43
GAA P10253 1/20 0.43
HPGD P15428 1/20 0.43
KMT2A Q03164 1/20 0.43
HSD17B10 Q99714 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14632437 1.00 F10 (0.53) F10F2PRSS1KDM4EMEN1
Hydrochloric Acid SCHEMBL14632408 0.99 F10 (0.52) F10F2PRSS1KDM4EMEN1
Hydrochloric Acid SCHEMBL14632406 0.99 F10 (0.52) F10F2PRSS1KDM4EMEN1
Hydrochloric Acid SCHEMBL14632606 0.95 F10 (0.50) F10F2PRSS1
Hydrochloric Acid SCHEMBL14632425 0.95 F10 (0.50) F10F2PRSS1
SCHEMBL10311098 0.80 ALOX5 (0.47) KDM4EMEN1ALDH1A1GAAHPGD
SCHEMBL5322918 0.80 F2 (0.47) F10F2PRSS1
SCHEMBL13603832 0.79 SMN1; SMN2 (0.46) MEN1ALDH1A1KMT2AHSD17B10
SCHEMBL8104378 0.79 SMN1; SMN2 (0.46) MEN1ALDH1A1KMT2AHSD17B10
SCHEMBL6502072 0.79 NOTUM (0.53) ALDH1A1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130023563-A1 AMIDINOANILINE DERIVATIVE AJINOMOTO CO., INC. (JP) 2013-01-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130023563-A1 AMIDINOANILINE DERIVATIVE F11, SERPINC1, F8 F10 17/4885F2 4/4885PRSS1 35/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.