Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | CTSV | O60911 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4836000 | 0.80 | ATM (0.43) | ALDH1A1KMT2AMEN1CYP1A2SMN1; SMN2 | |
| SCHEMBL4837329 | 0.80 | ATM (0.43) | ALDH1A1KMT2AMEN1CYP1A2SMN1; SMN2 | |
| SCHEMBL7238495 | 0.73 | ALDH1A1 (0.40) | ALDH1A1KMT2AMEN1CYP1A2SMN1; SMN2 | |
| SCHEMBL11350104 | 0.72 | DAO (0.51) | ALDH1A1KMT2AMEN1CYP1A2SMN1; SMN2 | |
| SCHEMBL9375285 | 0.71 | ERCC1 (0.62) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL3161729 | 0.70 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1CYP1A2SMN1; SMN2 | |
| SCHEMBL7237302 | 0.69 | RAB9A (0.37) | ALDH1A1CYP1A2SMN1; SMN2MAPTHPGD | |
| SCHEMBL5297105 | 0.69 | ALDH1A1 (0.36) | ALDH1A1KMT2AMEN1CYP1A2SMN1; SMN2 | |
| SCHEMBL5298458 | 0.69 | POLB (0.37) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL5299123 | 0.69 | PIM1 (0.40) | ALDH1A1KMT2ASMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | claimed |
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |