Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 6/20 | 0.44 |
| ▸ | MAOB | P27338 | 6/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | PTGIR | P43119 | 1/20 | 0.40 |
| ▸ | RHEB | Q15382 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL453913 | 0.87 | IDO1 (0.48) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL5322371 | 0.81 | GRM5 (0.40) | MEN1KMT2AALDH1A1RHEBIDO1 | |
| SCHEMBL3825516 | 0.81 | SLC6A4 (0.48) | ALDH1A1MAOAMAOBCHRNA7HSD17B10 | |
| SCHEMBL5326848 | 0.81 | MEN1 (0.47) | MEN1KMT2AALDH1A1L3MBTL1MAPT | |
| SCHEMBL4391356 | 0.80 | MAOB (0.48) | MEN1KMT2AALDH1A1MAOBIDO1 | |
| SCHEMBL5321798 | 0.77 | TERT (0.35) | ALDH1A1RHEB | |
| SCHEMBL481976 | 0.76 | MAOA (0.64) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL9476350 | 0.76 | MAOA (0.64) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL9475224 | 0.76 | MAOA (0.64) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL5473166 | 0.75 | CNR1 (0.40) | MEN1KMT2AALDH1A1IDO1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007114916-A2 | ARYLBENZYLPIPERIDINE COMPOUNDS | H. LUNDBECK A/S (DK) | 2007-10-11 | — | — | WO | disclosed |