Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.43 |
| ▸ | PPARA | Q07869 | 4/20 | 0.43 |
| ▸ | PPARD | Q03181 | 3/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 5/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5328614 | 0.84 | PPARG (0.50) | PPARGPPARAPPARDSYKL3MBTL1 | |
| SCHEMBL5323605 | 0.83 | BCL9 (0.47) | PPARGPPARAPPARDSYKCTSK | |
| SCHEMBL5323594 | 0.76 | PPARA (0.46) | PPARGPPARAPPARDMAPT | |
| SCHEMBL5320648 | 0.76 | PPARA (0.46) | PPARGPPARAPPARDMAPT | |
| SCHEMBL5325698 | 0.75 | PPARA (0.43) | PPARGPPARAPPARDMAPT | |
| SCHEMBL9765283 | 0.73 | LMNA (0.45) | SYKL3MBTL1CTSKCTSSCTSL | |
| SCHEMBL13073762 | 0.73 | LMNA (0.55) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL13073758 | 0.73 | LMNA (0.55) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL5328603 | 0.72 | PPARG (0.49) | PPARGPPARAPPARDCTSKCTSS | |
| SCHEMBL28746806 | 0.71 | LMNA (0.56) | SYKL3MBTL1CTSKCTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007118964-A1 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |
| WO-2007118963-A2 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |