Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 4/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 5/20 | 0.46 |
| ▸ | CTSL | P07711 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 3/20 | 0.45 |
| ▸ | CTSB | P07858 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5323605 | 0.88 | BCL9 (0.47) | PPARGADRB3SYKPPARAPPARD | |
| SCHEMBL13073762 | 0.85 | LMNA (0.55) | SYKCTSKCTSLCTSSCTSB | |
| SCHEMBL13073758 | 0.85 | LMNA (0.55) | SYKCTSKCTSLCTSSCTSB | |
| SCHEMBL9765305 | 0.84 | LMNA (0.51) | SYKCTSKCTSLCTSSCTSB | |
| SCHEMBL5323545 | 0.84 | PPARG (0.43) | PPARGADRB3SYKPPARAPPARD | |
| SCHEMBL5328603 | 0.83 | PPARG (0.49) | PPARGADRB3PPARAPPARDCTSK | |
| SCHEMBL9765290 | 0.82 | PTPN1 (0.55) | CTSKCA1CA2ACHECTSS | |
| SCHEMBL6557654 | 0.82 | CYP3A4 (0.49) | SYKCTSKCTSLCTSSCTSB | |
| SCHEMBL6185436 | 0.82 | LMNA (0.49) | SYKCTSKCTSLCTSSCTSB | |
| SCHEMBL8079357 | 0.80 | CYP3A4 (0.47) | SYKCTSKCTSLCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007118964-A1 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |