Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 5/20 | 0.43 |
| ▸ | CTSS | P25774 | 4/20 | 0.43 |
| ▸ | CTSL | P07711 | 3/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9513721 | 0.80 | LMNA (0.44) | LMNASMN1; SMN2CTSKCTSSCTSL | |
| SCHEMBL9765305 | 0.80 | LMNA (0.51) | LMNASMN1; SMN2CTSKCTSSCTSL | |
| SCHEMBL7998062 | 0.79 | TRPV1 (0.46) | LMNASMN1; SMN2HTT | |
| SCHEMBL13073758 | 0.78 | LMNA (0.55) | LMNASMN1; SMN2CTSKCTSSCTSL | |
| SCHEMBL13073762 | 0.78 | LMNA (0.55) | LMNASMN1; SMN2CTSKCTSSCTSL | |
| SCHEMBL23786503 | 0.76 | LMNA (0.56) | LMNASMN1; SMN2CTSKCTSSCTSL | |
| SCHEMBL9293928 | 0.76 | LMNA (0.59) | LMNASMN1; SMN2CTSKCTSSCTSL | |
| SCHEMBL9512030 | 0.76 | CA1 (0.54) | LMNASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL1554044 | 0.75 | CA1 (0.47) | LMNASMN1; SMN2CTSKCTSSCTSL | |
| SCHEMBL4473071 | 0.75 | LMNA (0.58) | LMNASMN1; SMN2CTSKCTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255728-B1 | PHENOXYACETIC ACID COMPOUNDS, THEIR PREPARATION, PHARMACEUTICAL COMPOSITION AND USE | TANABE SEIYAKU CO., LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |
| US-4866196-A | ANTICOAGULANTS | TANABE SEIYAKU CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| EP-0255728-A2 | Phenoxyacetic acid compounds, their preparation, pharmaceutical composition and use | TANABE SEIYAKU CO., LTD. (JP) | 1988-02-10 | — | — | EP | disclosed |