Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 1/20 | 0.86 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.84 |
| ▸ | PKM | P14618 | 1/20 | 0.84 |
| ▸ | TP53 | P04637 | 5/20 | 0.81 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 7/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | AURKB | Q96GD4 | 5/20 | 0.60 |
| ▸ | AURKA | O14965 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | MC4R | P32245 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | CLK1 | P49759 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325876 | 0.96 | TP53 (0.81) | CREBBPKDM4EALDH1A1PKMTP53 | |
| SCHEMBL4749262 | 0.91 | TP53 (0.75) | CREBBPKDM4EALDH1A1PKMTP53 | |
| SCHEMBL5329104 | 0.90 | CREBBP (0.82) | CREBBPKDM4EALDH1A1PKMTP53 | |
| SCHEMBL5322774 | 0.90 | CREBBP (0.82) | CREBBPKDM4EALDH1A1PKMTP53 | |
| SCHEMBL5328005 | 0.90 | PAX8 (0.83) | CREBBPKDM4EALDH1A1PKMTP53 | |
| SCHEMBL23493740 | 0.90 | TP53 (1.00) | CREBBPKDM4EALDH1A1PKMTP53 | |
| SCHEMBL31307876 | 0.90 | TP53 (1.00) | CREBBPKDM4EALDH1A1PKMTP53 | |
| SCHEMBL5325640 | 0.89 | PAX8 (0.85) | CREBBPKDM4EALDH1A1PKMTP53 | |
| SCHEMBL5323500 | 0.89 | CREBBP (0.79) | CREBBPKDM4EALDH1A1PKMTP53 | |
| SCHEMBL23494146 | 0.89 | TP53 (0.88) | CREBBPKDM4EALDH1A1PKMTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007139496-A1 | QUINOLINE DERIVATIVES ACTING AS TYROSINE KINASE INHIBITORS | CLANOTECH AB (SE) | 2007-12-06 | — | — | WO | disclosed |