Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | MC5R | P33032 | 1/20 | 0.40 |
| ▸ | MC3R | P41968 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325028 | 0.91 | ALDH1A1 (0.42) | BACE1ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL5326162 | 0.89 | ALDH1A1 (0.46) | ALDH1A1MAPTLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL5321280 | 0.87 | ICMT (0.46) | ALDH1A1MAPTLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL5323221 | 0.87 | MAPT (0.45) | ALDH1A1MAPTLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL5328167 | 0.87 | MAPT (0.44) | ALDH1A1MAPTLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL5325721 | 0.86 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL5328217 | 0.86 | MAPT (0.43) | ALDH1A1MAPTLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL5321277 | 0.86 | MAPT (0.42) | ALDH1A1MAPTLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL5328172 | 0.86 | MAPT (0.41) | ALDH1A1MAPTLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL5326617 | 0.85 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007115231-A2 | CXCR4 MODULATORS | CHEMOCENTRYX, INC. (US) | 2007-10-11 | — | — | WO | disclosed |