Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | CCR3 | P51677 | 2/20 | 0.44 |
| ▸ | MLNR | O43193 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14337866 | 0.82 | MAPK14 (0.59) | MAPK14MLNRCYP3A4HSD11B1 | |
| SCHEMBL5318563 | 0.80 | EPHX2 (0.52) | EPHX2ADRB2HRH1CCR3MLNR | |
| SCHEMBL5317962 | 0.78 | HPGD (0.50) | EPHX2ADRB2HRH1CCR3MLNR | |
| SCHEMBL5317983 | 0.78 | ADRB2 (0.46) | MAPK14EPHX2ADRB2MLNRCYP3A4 | |
| SCHEMBL14467014 | 0.78 | MAPK14 (0.58) | MAPK14EPHX2 | |
| SCHEMBL5321693 | 0.77 | EPHX2 (0.49) | EPHX2ADRB2HRH1CCR3MLNR | |
| SCHEMBL1807163 | 0.76 | CHRNA7 (0.56) | CHRNA7 | |
| SCHEMBL1807186 | 0.76 | HRH3 (0.51) | CHRNA7 | |
| SCHEMBL14466895 | 0.76 | PRKAA2 (0.51) | EPHX2ADRB2HRH1CCR3MLNR | |
| SCHEMBL5323904 | 0.74 | EPHX2 (0.48) | EPHX2ADRB2HRH1CCR3MLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007082079-A2 | PIPERIDINE AMIDE DERIVATIVES AS PROTEIN KINASE INHIBITORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-07-19 | — | — | WO | disclosed |