Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 4/20 | 0.49 |
| ▸ | CCR3 | P51677 | 4/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.47 |
| ▸ | MLNR | O43193 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5317962 | 0.86 | HPGD (0.50) | EPHX2ADRB2HRH1CCR3HSD11B1 | |
| SCHEMBL5323904 | 0.84 | EPHX2 (0.48) | EPHX2ADRB2HRH1CCR3HSD11B1 | |
| SCHEMBL14466895 | 0.84 | PRKAA2 (0.51) | EPHX2ADRB2HRH1CCR3HSD11B1 | |
| SCHEMBL5321693 | 0.83 | EPHX2 (0.49) | EPHX2ADRB2HRH1CCR3HSD11B1 | |
| SCHEMBL4603720 | 0.81 | RAB9A (0.59) | EPHX2HRH1CCR3HSD11B1GAA | |
| SCHEMBL5323974 | 0.81 | MAPK14 (0.57) | CCR3MLNRCYP3A4 | |
| SCHEMBL5323864 | 0.80 | MAPK14 (0.49) | EPHX2ADRB2HRH1CCR3HSD11B1 | |
| SCHEMBL14466901 | 0.80 | GRIN2D (0.55) | EPHX2ADRB2HRH1CCR3SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5321355 | 0.80 | MAPK14 (0.56) | CCR3MLNRCYP3A4 | |
| SCHEMBL14467021 | 0.79 | EPHX2 (0.46) | EPHX2ADRB2HRH1CCR3MLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007082079-A2 | PIPERIDINE AMIDE DERIVATIVES AS PROTEIN KINASE INHIBITORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-07-19 | — | — | WO | disclosed |