Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | TRPC6 | Q9Y210 | 5/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.46 |
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | CCR3 | P51677 | 2/20 | 0.44 |
| ▸ | MLNR | O43193 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5318563 | 0.84 | EPHX2 (0.52) | EPHX2ADRB2HRH1CCR3MLNR | |
| SCHEMBL14466887 | 0.83 | PRKAA2 (0.49) | EPHX2ADRB2PRKAA2HRH1CCR3 | |
| SCHEMBL5317962 | 0.83 | HPGD (0.50) | EPHX2ADRB2HRH1CCR3MLNR | |
| SCHEMBL5342932 | 0.80 | ADRB2 (0.47) | EPHX2ADRB2PRKAA2HRH1CCR3 | |
| SCHEMBL5321693 | 0.80 | EPHX2 (0.49) | EPHX2ADRB2HRH1CCR3MLNR | |
| SCHEMBL14467022 | 0.79 | EPHX2 (0.44) | EPHX2ADRB2PRKAA2HRH1CCR3 | |
| SCHEMBL14466895 | 0.76 | PRKAA2 (0.51) | EPHX2ADRB2PRKAA2HRH1CCR3 | |
| SCHEMBL5323864 | 0.74 | MAPK14 (0.49) | EPHX2ADRB2HRH1CCR3MLNR | |
| SCHEMBL1809345 | 0.74 | ADRB2 (0.71) | ADRB2HRH1HSD11B1 | |
| SCHEMBL1809547 | 0.73 | EPHX2 (0.52) | EPHX2ADRB2HRH1CCR3MLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007082079-A2 | PIPERIDINE AMIDE DERIVATIVES AS PROTEIN KINASE INHIBITORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-07-19 | — | — | WO | disclosed |