Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 5/20 | 0.45 |
| ▸ | SMAD3 | P84022 | 3/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | BAG3 | O95817 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5323121 | 0.81 | ALDH1A1 (0.43) | P4HBSMAD3KCNA5CYP3A4TSHR | |
| SCHEMBL12248160 | 0.75 | KCNA5 (0.46) | P4HBSMAD3KCNA5CYP3A4TSHR | |
| SCHEMBL11375744 | 0.74 | P4HB (0.51) | P4HBSMAD3KCNA5CYP3A4TSHR | |
| SCHEMBL7745378 | 0.73 | DPP4 (0.46) | P4HBSMAD3KCNA5CYP3A4TSHR | |
| SCHEMBL4105367 | 0.73 | DPP4 (0.62) | KCNA5CYP3A4TSHRCYP2C19ALDH1A1 | |
| SCHEMBL13553401 | 0.72 | P4HB (0.52) | P4HBSMAD3KCNA5CYP3A4TSHR | |
| SCHEMBL5681454 | 0.72 | HSP90AA1 (0.45) | P4HBSMAD3KCNA5CYP3A4TSHR | |
| SCHEMBL11955271 | 0.72 | ALOX12 (0.67) | P4HBTSHRALDH1A1HSP90AA1MAPT | |
| SCHEMBL18108809 | 0.71 | ALDH1A1 (0.41) | KCNA5CYP3A4TSHRCYP2C19ALDH1A1 | |
| SCHEMBL16463458 | 0.71 | ALDH1A1 (0.47) | KCNA5CYP3A4TSHRCYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007114672-A1 | AGENT FOR THE PREVENTION AND TREATMENT OF METABOLIC BONE DISEASE BY ENHANCING OSTEOPROTEGERIN SECRETION | OSCOTEC INC. (KR) | 2007-10-11 | — | — | WO | disclosed |