SCHEMBL5323933

SCHEMBL5323933

N#CCc1ccc(C(=O)c2ccc(CC#N)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.49
MEN1 O00255 5/20 0.43
ALDH1A1 P00352 5/20 0.43
MAPT P10636 4/20 0.43
HPGD P15428 3/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
LMNA P02545 5/20 0.42
SRD5A2 P31213 5/20 0.42
HTT P42858 2/20 0.42
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
PKM P14618 1/20 0.42
NPC1 O15118 4/20 0.41
RAB9A P51151 3/20 0.41
POLB P06746 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
ALPG P10696 1/20 0.40
THRB P10828 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7492979 0.92 KMT2A (0.54) KMT2AMEN1ALDH1A1MAPTHPGD
SCHEMBL211305 0.84 ALDH1A1 (0.54) KMT2AMEN1ALDH1A1MAPTSMN1; SMN2
SCHEMBL1032852 0.83 PLA2G10 (0.52) KMT2AMEN1ALDH1A1MAPTSMN1; SMN2
SCHEMBL9142779 0.83 KMT2A (0.59) KMT2AMEN1ALDH1A1MAPTHPGD
SCHEMBL7039295 0.83 KMT2A (0.46) KMT2AMEN1ALDH1A1MAPTHPGD
SCHEMBL2154504 0.80 KMT2A (0.47) KMT2AMEN1MAPTLMNAHTT
SCHEMBL3634999 0.79 RARB (0.51) KMT2AMEN1ALDH1A1MAPTSRD5A2
SCHEMBL9195660 0.79 GSK3B (0.53) KMT2AMEN1ALDH1A1MAPTHPGD
SCHEMBL11706226 0.79 HPGDS (0.57) KMT2AMEN1ALDH1A1MAPTHPGD
SCHEMBL3681754 0.78 NPC1 (0.45) KMT2AMEN1SRD5A2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101124516-A Pattern forming material, pattern forming apparatus, and pattern forming method FUJI FILM CORP (JP) 2008-02-13 CN disclosed
WO-2007139240-A1 7-(3,4-DIALKOXYPHENYL)-PYRAZOLO[1,5-A]PYRIMIDINE COMPOUNDS, PROCESS FOR PREPARING THEREOF, AND PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING ASTHMA, CHRONIC OBSTRUCTIVE PULMONARY DISEASE, ARTHRITIS, ATOPIC DERMATITIS, TUMOR AND DEGENERATIVE BRAIN DISEASES COMPRISING THE SAME KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2007-12-06 WO disclosed
US-5667958-A METALLOCENE COMPOUND ATTACHED TO METHINE DYE, NONFOGGING, STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1997-09-16 US disclosed
US-5578440-A Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1996-11-26 US disclosed
US-5527914-A STORAGE STABLE MEROCYANINE DYES; ANTIFOGGING; FOR USE IN SILVER HALIDE PHOTOGRAPHY, OPTICAL RECORDING MEDIA, DRUGS FUJI PHOTO FILM CO., LTD. (JP) 1996-06-18 US disclosed
US-5340710-A Improved sensitivity KONICA CORPORATION (JP) 1994-08-23 US disclosed
US-5242790-A Photographic films with silver halide emulsions and cyanine dyes FUJI PHOTO FILM CO., LTD. (JP) 1993-09-07 US disclosed
US-5166047-A Storage stable photographic emulsions with antifogging ability FUJI PHOTO FILM CO. LTD. (JP) 1992-11-24 US disclosed
EP-0323215-A2 Photosensitive silver halide photographic material KONICA CORPORATION (JP) 1989-07-05 EP disclosed