SCHEMBL211305

SCHEMBL211305

N#CCc1ccc(C(=O)O)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
TSHR P16473 2/20 0.52
TP53 P04637 1/20 0.52
KMT2A Q03164 3/20 0.47
SRD5A2 P31213 3/20 0.46
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA12 O43570 1/20 0.44
CA3 P07451 1/20 0.44
TYR P14679 1/20 0.44
DRD1 P21728 1/20 0.44
CA4 P22748 1/20 0.44
CA6 P23280 1/20 0.44
CA5A P35218 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44
CA5B Q9Y2D0 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
KDM4E B2RXH2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3634999 0.94 RARB (0.51) ALDH1A1TSHRTP53KMT2ASRD5A2
Terephthalic Acid SCHEMBL10902761 0.92 TSHR (0.53) ALDH1A1TSHRTP53KMT2ASRD5A2
SCHEMBL5323933 0.84 KMT2A (0.49) ALDH1A1KMT2ASRD5A2SMN1; SMN2MEN1
SCHEMBL7492979 0.82 KMT2A (0.54) ALDH1A1KMT2ASRD5A2SMN1; SMN2MEN1
SCHEMBL30369998 0.81 GRIN2D (0.51) ALDH1A1KMT2AKDM4EMEN1TDP1
SCHEMBL21750392 0.81 GRIN2D (0.51) ALDH1A1KMT2AKDM4EMEN1TDP1
SCHEMBL1032852 0.81 PLA2G10 (0.52) ALDH1A1TSHRKMT2ACA1CA2
SCHEMBL9142779 0.81 KMT2A (0.59) ALDH1A1KMT2ASMN1; SMN2MEN1GAA
SCHEMBL7039295 0.81 KMT2A (0.46) ALDH1A1KMT2ACA1CA2SMN1; SMN2
SCHEMBL6538715 0.80 ALDH1A1 (0.56) ALDH1A1TSHRTP53KMT2ASRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119306978-A Preparation method of nylon 6 composite material 湖南工业大学 2025-01-14 CN claimed
CN-116836081-A Ether epoxy toughening agent and preparation method and application thereof 中国林业科学研究院林产化学工业研究所 2023-10-03 CN claimed
US-7364882-B1 Enzymatic reduction of a nitrile containing compound to the corresponding amine STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF PORTLAND STATE UNIVERSITY (US) 2008-04-29 US claimed
US-20250346616-A1 ROCK INHIBITORS AND USES THEREOF DIZAL JIANGSU PHARMACEUTICAL CO LTD (CN) 2025-11-13 US disclosed
EP-4532484-A1 ROCK INHIBITORS AND USES THEREOF DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) 2025-04-09 EP disclosed
CN-119306978-A Preparation method of nylon 6 composite material 湖南工业大学 2025-01-14 CN disclosed
CN-118853682-A Novel DNA nucleic acid aptamer molecule, and compound and application thereof 华东理工大学 2024-10-29 CN disclosed
CN-118853680-A Novel DNA nucleic acid aptamer molecule, and compound and application thereof 华东理工大学 2024-10-29 CN disclosed
WO-2023226965-A1 ROCK INHIBITORS AND USES THEREOF DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) 2023-11-30 WO disclosed
US-20230348386-A1 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF RAZE THERAPEUTICS, INC. 2023-11-02 US disclosed
CN-116836081-A Ether epoxy toughening agent and preparation method and application thereof 中国林业科学研究院林产化学工业研究所 2023-10-03 CN disclosed
EP-0358118-A1 Phenylamides - process for their preparation as well as a drug containing those compounds Roche Diagnostics GmbH (DE) 1990-03-14 EP disclosed
US-4814346-A Benzopyrans and use thereof in treating vascular diseases ZYMA SA (CH) 1989-03-21 US disclosed
EP-0267155-A2 Bicyclic compounds Zyma SA (CH) 1988-05-11 EP disclosed
US-4735959-A HYPOGLYCEMIC AGENTS DR. KARL THOMAE GMBH (DE) 1988-04-05 US disclosed
EP-0099017-B1 PHENYL-ACETIC-ACID DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSTIONS CONTAINING THEM Dr. Karl Thomae GmbH (DE) 1988-03-02 EP disclosed
EP-0099017-A2 Phenyl-acetic-acid derivatives, their preparation and pharmaceutical compostions containing them Dr. Karl Thomae GmbH (DE) 1984-01-25 EP disclosed
US-4324792-A SKIN DISORDERS, HAY FEVER, ASTHMA GLAXO GROUP LIMITED (GB) 1982-04-13 US disclosed
US-4131677-A Anti-inflammatory oxazolo [5,4-b]pyridines MERCK & CO., INC. (US) 1978-12-26 US disclosed
US-4038396-A ANTIPYRETICS, ANALGESICS MERCK & CO., INC. (US) 1977-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348386-A1 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF PHGDH, G6PD, PGD ALDH1A1 222/4885TSHR 4686/4885TP53 1530/4885
US-20250346616-A1 ROCK INHIBITORS AND USES THEREOF ROCK1, ROCK2, RHOA ALDH1A1 2229/4885TSHR 3777/4885TP53 3901/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.