Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 20/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5431957 | 0.87 | HTR6 (0.54) | HTR6CYP3A4ADRA2ACYP2D6ADRA2C | |
| SCHEMBL5332274 | 0.86 | HTR6 (0.55) | HTR6CYP3A4ADRA2ACYP2D6ADRA2C | |
| SCHEMBL5331844 | 0.84 | HTR6 (0.56) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL5304701 | 0.81 | HTR6 (0.49) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL5327454 | 0.79 | HTR6 (0.58) | HTR6CYP3A4CYP2D6HTR2A | |
| SCHEMBL949734 | 0.78 | HTR6 (0.70) | HTR6CYP3A4ADRA2ACYP2D6ADRA2C | |
| SCHEMBL947301 | 0.78 | HTR6 (0.70) | HTR6CYP3A4ADRA2ACYP2D6ADRA2C | |
| SCHEMBL5327431 | 0.78 | HTR6 (0.58) | HTR6 | |
| SCHEMBL4772681 | 0.77 | HTR6 (0.60) | HTR6CYP3A4ADRA2ACYP2D6ADRA2C | |
| SCHEMBL5230698 | 0.75 | HTR6 (0.78) | HTR6CYP3A4ADRA2ACYP2D6ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | claimed |
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | disclosed |