Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 9/20 | 0.45 |
| ▸ | CNR1 | P21554 | 6/20 | 0.43 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 3/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5347503 | 0.85 | NR4A2 (0.46) | FYNCNR1DPP4DPP8DPP9 | |
| SCHEMBL5336486 | 0.80 | AKT1 (0.39) | CNR1DPP4DPP8DPP9 | |
| SCHEMBL5336981 | 0.76 | MAPT (0.41) | CNR1DPP4DPP8DPP9 | |
| SCHEMBL5341370 | 0.76 | MAP4K4 (0.52) | — | |
| SCHEMBL5320273 | 0.76 | DPP4 (0.52) | DPP4DPP8DPP9 | |
| SCHEMBL5344323 | 0.75 | CYP3A4 (0.44) | CNR1DPP4DPP8DPP9 | |
| SCHEMBL5345483 | 0.75 | NR4A2 (0.51) | FYN | |
| SCHEMBL5352678 | 0.75 | AKT1 (0.43) | CNR1DPP4DPP8DPP9 | |
| SCHEMBL5343498 | 0.73 | FYN (0.46) | FYN | |
| SCHEMBL5325683 | 0.72 | AKT1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096764-A2 | BICYCLIC HETEROARYL DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-08-30 | — | — | WO | claimed |
| WO-2007096764-A2 | BICYCLIC HETEROARYL DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-08-30 | — | — | WO | disclosed |