Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5342992 | 0.90 | MAPT (0.45) | MAPTKDM4ENPSR1L3MBTL1KMT2A | |
| SCHEMBL5336486 | 0.83 | AKT1 (0.39) | MAPTKDM4EKMT2AMEN1RAB9A | |
| SCHEMBL5347503 | 0.81 | NR4A2 (0.46) | MAPK1CNR1CYP1A2CYP2C19RPS6KA3 | |
| SCHEMBL5320273 | 0.81 | DPP4 (0.52) | MAPTL3MBTL1KMT2AMEN1RAB9A | |
| SCHEMBL5344323 | 0.80 | CYP3A4 (0.44) | KDM4ENPSR1RAB9ASLC2A1CNR1 | |
| SCHEMBL5352678 | 0.80 | AKT1 (0.43) | MAPTKDM4EL3MBTL1KMT2ARAB9A | |
| SCHEMBL5325683 | 0.77 | AKT1 (0.51) | MAPTKDM4EL3MBTL1KMT2ARAB9A | |
| SCHEMBL5320900 | 0.77 | DPP4 (0.52) | MAPTL3MBTL1KMT2ASLC2A1CYP1A2 | |
| SCHEMBL5324489 | 0.76 | FYN (0.45) | CNR1DPP4DPP8DPP9 | |
| SCHEMBL5348641 | 0.76 | DPP4 (0.39) | MAPTKDM4EL3MBTL1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096764-A2 | BICYCLIC HETEROARYL DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-08-30 | — | — | WO | disclosed |