Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | VDR | P11473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL156226 | 0.81 | MMP2 (0.41) | LMNACA12CYP3A4CA9PTPN1 | |
| SCHEMBL7993483 | 0.78 | BCHE (0.45) | LMNABCHEACHECA12CYP1A2 | |
| SCHEMBL605141 | 0.78 | PPARG (0.47) | LMNABCHEACHECA12CYP1A2 | |
| SCHEMBL7354211 | 0.77 | BCHE (0.44) | LMNABCHEACHECA12CYP1A2 | |
| SCHEMBL7334079 | 0.75 | FDPS (0.50) | FDPSPTPN1 | |
| SCHEMBL10710616 | 0.75 | BCHE (0.40) | LMNABCHEACHECA12CYP1A2 | |
| SCHEMBL23581205 | 0.72 | MMP2 (0.46) | LMNABCHEACHECA12CYP1A2 | |
| SCHEMBL22945552 | 0.71 | BCHE (0.41) | LMNABCHEACHECA12CYP1A2 | |
| SCHEMBL16020646 | 0.71 | TSHR (0.47) | LMNABCHEACHECA12CYP1A2 | |
| SCHEMBL6230138 | 0.71 | RECQL (0.49) | LMNAMAPTKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007112348-A2 | PRODRUG COMPOSITION | TSRL, INC. (US) | 2007-10-04 | — | — | WO | disclosed |
| US-20070167353-A1 | PRODRUG COMPOSITION | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2007-07-19 | — | — | US | disclosed |
| US-20050137141-A1 | Prodrug composition | HILFINGER JOHN (US) | 2005-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167353-A1 | PRODRUG COMPOSITION | ADA, SLC29A1, SLC29A2 | LMNA 3606/4885FDPS 824/4885BCHE 707/4885 |
| US-20050137141-A1 | Prodrug composition | CYP3A5, SLC35B2, SLC1A5 | LMNA 3095/4885FDPS 994/4885BCHE 588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.