Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | MITF | O75030 | 2/20 | 0.61 |
| ▸ | XBP1 | P17861 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.59 |
| ▸ | HTT | P42858 | 5/20 | 0.59 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | RNF4 | P78317 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 2/20 | 0.50 |
| ▸ | CASP2 | P42575 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9081388 | 0.87 | NPC1 (0.76) | NPC1RAB9AMITFXBP1NPSR1 | |
| SCHEMBL5324688 | 0.85 | SMN1; SMN2 (0.65) | NPC1RAB9AMITFXBP1NPSR1 | |
| SCHEMBL6287639 | 0.80 | CA1 (0.58) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2635734 | 0.79 | NPC1 (0.66) | NPC1RAB9AMITFXBP1NPSR1 | |
| SCHEMBL16922181 | 0.79 | NPC1 (0.66) | NPC1RAB9AMITFXBP1NPSR1 | |
| SCHEMBL1503954 | 0.79 | NPC1 (0.66) | NPC1RAB9AMITFXBP1NPSR1 | |
| SCHEMBL14003727 | 0.78 | TSHR (0.70) | RAB9AALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL2320435 | 0.78 | NPC1 (0.63) | NPC1RAB9AMITFXBP1NPSR1 | |
| SCHEMBL5903996 | 0.78 | ALDH1A1 (0.67) | NPC1RAB9AMITFXBP1NPSR1 | |
| SCHEMBL1193345 | 0.78 | NPC1 (0.63) | NPC1RAB9AMITFXBP1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0217256-B1 | METHOD FOR QUENCHING FLUORESCENCE, AND CATIONIC DERIVATIVES OF NAPHTHALENE-PERI-DICARBOXAMIDE | BAYER AG (DE) | 1991-03-06 | — | — | EP | disclosed |
| EP-0163854-B1 | PROCESS FOR THE ELIMINATION OF FLUORESCENCE AND CATIONIC OR AMPHOTERIC AROMATIC NITRO COMPOUNDS | BAYER AG (DE) | 1991-02-27 | — | — | EP | disclosed |
| US-4919848-A | Process for the quenching of fluorescence, and new cationic naphthalene-peri-dicarboxylic acid imide derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1990-04-24 | — | — | US | disclosed |
| US-4695405-A | Process for quenching fluorescence, and new cationic or amphoteric aromatic nitro compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1987-09-22 | — | — | US | disclosed |
| EP-0217256-A2 | Method for quenching fluorescence, and cationic derivatives of naphthalene-peri-dicarboxamide | BAYER AG (DE) | 1987-04-08 | — | — | EP | disclosed |
| EP-0163854-A2 | Process for the elimination of fluorescence and cationic or amphoteric aromatic nitro compounds | BAYER AG (DE) | 1985-12-11 | — | — | EP | disclosed |