Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 6/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31267284 | 0.80 | MEN1 (0.40) | MEN1KMT2AL3MBTL1KDM4CNPC1 | |
| SCHEMBL411707 | 0.79 | MEN1 (0.41) | MEN1KMT2AL3MBTL1KDM4CNPC1 | |
| SCHEMBL12634797 | 0.77 | ALDH1A1 (0.55) | MEN1KMT2AL3MBTL1KDM4CNPC1 | |
| SCHEMBL8509829 | 0.76 | MEN1 (0.44) | MEN1KMT2AL3MBTL1KDM4CNPC1 | |
| SCHEMBL5883038 | 0.76 | MEN1 (0.38) | MEN1KMT2AL3MBTL1KDM4CNPC1 | |
| SCHEMBL5883537 | 0.75 | MEN1 (0.40) | MEN1KMT2AL3MBTL1KDM4CNPC1 | |
| SCHEMBL31267334 | 0.74 | L3MBTL1 (0.41) | MEN1KMT2AL3MBTL1KDM4CNPC1 | |
| SCHEMBL31267424 | 0.74 | L3MBTL1 (0.41) | MEN1KMT2AL3MBTL1KDM4CNPC1 | |
| SCHEMBL4119494 | 0.73 | MEN1 (0.58) | MEN1KMT2AL3MBTL1KDM4CNPC1 | |
| SCHEMBL1704820 | 0.72 | ICAM1 (0.39) | MEN1KMT2AL3MBTL1KDM4CNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007002325-A1 | PYRROLO[2,3-B] PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | PLEXXIKON, INC. (US) | 2007-01-04 | — | — | WO | disclosed |