Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5324544 | 0.91 | POLB (0.55) | POLBMAPTNPSR1HTTALDH1A1 | |
| SCHEMBL5327188 | 0.89 | THRB (0.39) | MAPTHTTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5329550 | 0.82 | THRB (0.39) | POLBMAPTNPSR1ALDH1A1HPGD | |
| SCHEMBL5326106 | 0.82 | F2 (0.36) | POLBMAPTLMNAKDM4ENPBWR1 | |
| SCHEMBL5330286 | 0.79 | THRB (0.49) | POLBNPSR1HTTALDH1A1HPGD | |
| SCHEMBL5398709 | 0.79 | THRB (0.42) | POLBMAPTALDH1A1KDM4E | |
| SCHEMBL5415371 | 0.77 | THRB (0.45) | MAPTHTTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL5328999 | 0.77 | THRB (0.52) | NPSR1ALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL5324510 | 0.76 | THRB (0.38) | MAPTNPSR1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL5326299 | 0.76 | L3MBTL1 (0.49) | POLBNPSR1ALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007132475-A1 | SELECTIVE TR-BETA 1 AGONIST | CADILA HEALTHCARE LIMITED (IN) | 2007-11-22 | — | — | WO | claimed |
| WO-2007132475-A1 | SELECTIVE TR-BETA 1 AGONIST | CADILA HEALTHCARE LIMITED (IN) | 2007-11-22 | — | — | WO | disclosed |