Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332095 | 0.88 | THRB (0.63) | THRBTHRAALDH1A1HPGDGAA | |
| SCHEMBL5326106 | 0.84 | F2 (0.36) | THRBTHRAPOLBLMNAKDM4E | |
| SCHEMBL5324544 | 0.82 | POLB (0.55) | ALDH1A1HPGDPOLBKMT2AMEN1 | |
| SCHEMBL5328999 | 0.82 | THRB (0.52) | THRBALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL5328482 | 0.81 | ALDH1A1 (0.52) | THRBALDH1A1HPGDGAAPOLB | |
| SCHEMBL5324978 | 0.79 | POLB (0.43) | ALDH1A1HPGDPOLBLMNAHTT | |
| SCHEMBL7041996 | 0.79 | ALDH1A1 (0.50) | THRBTHRAALDH1A1HPGDGAA | |
| SCHEMBL5324510 | 0.78 | THRB (0.38) | THRBTHRAALDH1A1LMNAHTT | |
| SCHEMBL5329550 | 0.78 | THRB (0.39) | THRBTHRAALDH1A1HPGDGAA | |
| SCHEMBL5330302 | 0.78 | MEN1 (0.48) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007132475-A1 | SELECTIVE TR-BETA 1 AGONIST | CADILA HEALTHCARE LIMITED (IN) | 2007-11-22 | — | — | WO | disclosed |