Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6421403 | 0.84 | TSHR (0.46) | ALOX5EPHX2TSHRLMNAALDH1A1 | |
| SCHEMBL14074885 | 0.77 | TSHR (0.49) | EPHX2TSHRLMNAALDH1A1SLC1A3 | |
| SCHEMBL27942402 | 0.74 | TSHR (0.41) | ALOX5EPHX2TSHRLMNAALDH1A1 | |
| SCHEMBL14074876 | 0.72 | TSHR (0.45) | TSHRLMNAALDH1A1POLBKMT2A | |
| SCHEMBL2469547 | 0.71 | MAOA (0.50) | TSHRLMNAALDH1A1 | |
| SCHEMBL30589493 | 0.71 | MAOA (0.50) | TSHRLMNAALDH1A1 | |
| SCHEMBL2100052 | 0.70 | — | — | |
| Furfuryl Alcohol SCHEMBL1487380 | 0.70 | ALOX5 (0.56) | ALOX5EPHX2ALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL13280659 | 0.69 | TSHR (0.41) | ALOX5EPHX2TSHRLMNAALDH1A1 | |
| SCHEMBL17033080 | 0.68 | ALDH1A1 (0.40) | EPHX2TSHRLMNAALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007136640-A2 | PROCESSES FOR THE PREPARATION OF SUBSTITUTED 2-(2,6-DIOXOPIPERIDIN-3-YL)ISOINDOLE-1,3-DIONE | CELGENE CORPORATION (US) | 2007-11-29 | — | — | WO | disclosed |