Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4483467 | 0.87 | MMP13 (0.59) | MMP13HPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL4977146 | 0.86 | ALDH1A1 (0.65) | MMP13HPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL29936927 | 0.84 | CA1 (0.66) | MMP13HPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL14797152 | 0.82 | MMP13 (0.58) | MMP13HPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL14724810 | 0.82 | GAA (0.62) | MMP13HPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL30780038 | 0.82 | GAA (0.62) | MMP13HPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL4926491 | 0.82 | CFD (0.57) | HPGDHSP90AA1LMNASENP1IDO1 | |
| SCHEMBL3816878 | 0.82 | HPGD (0.79) | MMP13HPGDALDH1A1KDM4ELMNA | |
| SCHEMBL3037056 | 0.82 | HDAC8 (0.65) | MMP13HPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8042301 | 0.81 | HDAC6 (0.77) | HPGDALDH1A1HSP90AA1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007131996-A1 | META-XYLYLENEDIAMINE VANADATE SALTS | GENMEDICA THERAPEUTICS SL (ES) | 2007-11-22 | — | — | WO | disclosed |