Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.55 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | TK2 | O00142 | 9/20 | 0.41 |
| ▸ | TK1 | P04183 | 1/20 | 0.40 |
| ▸ | DUT | P33316 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5323607 | 0.94 | KIF11 (0.53) | KIF11HRH4TK2TK1DUT | |
| SCHEMBL5326522 | 0.93 | KIF11 (0.52) | KIF11HRH4TK2TK1DUT | |
| SCHEMBL9371526 | 0.90 | KIF11 (0.57) | KIF11HRH4TK2TK1DUT | |
| SCHEMBL260513 | 0.83 | KIF11 (0.53) | KIF11HRH4TK2TK1DUT | |
| SCHEMBL11275984 | 0.79 | KIF11 (0.74) | KIF11HRH4TK2TK1DUT | |
| SCHEMBL5324252 | 0.78 | KIF11 (0.50) | KIF11HRH4TK2TK1DUT | |
| SCHEMBL22128493 | 0.77 | KIF11 (0.50) | KIF11HRH4TK2TK1DUT | |
| SCHEMBL2489713 | 0.76 | KIF11 (0.59) | KIF11HRH4TK2TK1DUT | |
| SCHEMBL913478 | 0.76 | KIF11 (0.59) | KIF11HRH4TK2TK1DUT | |
| SCHEMBL5282316 | 0.76 | KIF11 (0.59) | KIF11HRH4TK2TK1DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827423-B1 | FUNCTIONALIZED CHAIN EXTENDED INITIATORS FOR ANIONIC POLYMERIZATION | FMC CORP (US) | 2007-12-12 | — | — | EP | claimed |