Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.57 |
| ▸ | CES1 | P23141 | 3/20 | 0.57 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4707612 | 0.83 | CES2 (0.59) | CES2CES1ACKR3L3MBTL1GAA | |
| SCHEMBL31529633 | 0.81 | CES2 (0.61) | CES2CES1ACKR3L3MBTL1GAA | |
| SCHEMBL19104747 | 0.81 | CES2 (0.61) | CES2CES1ACKR3L3MBTL1GAA | |
| SCHEMBL108531 | 0.81 | CES2 (0.61) | CES2CES1L3MBTL1GAASNCA | |
| Hydrochloric Acid SCHEMBL30444188 | 0.79 | CES2 (0.59) | CES2CES1ACKR3L3MBTL1GAA | |
| Hydrochloric Acid SCHEMBL19817282 | 0.79 | CES2 (0.59) | CES2CES1ACKR3L3MBTL1GAA | |
| SCHEMBL25208513 | 0.79 | CES2 (0.53) | CES2CES1ACKR3L3MBTL1GAA | |
| SCHEMBL1924321 | 0.79 | PLOD2 (0.59) | CES2CES1ACKR3L3MBTL1SNCA | |
| SCHEMBL8584 | 0.79 | CES2 (0.63) | CES2CES1ACKR3L3MBTL1SNCA | |
| SCHEMBL293958 | 0.78 | CES2 (0.68) | CES2CES1L3MBTL1GAADGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007118853-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS BLOCKERS OF CALCIUM CHANNELS | EURO-CELTIQUE S.A. (LU) | 2007-10-25 | — | — | WO | disclosed |