Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.63 |
| ▸ | CES1 | P23141 | 3/20 | 0.63 |
| ▸ | ACKR3 | P25106 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27764538 | 0.83 | CES2 (0.63) | CES2CES1 | |
| SCHEMBL29746067 | 0.82 | CES2 (0.61) | CES2CES1ACKR3L3MBTL1KCNH2 | |
| SCHEMBL13959406 | 0.82 | CES2 (0.61) | CES2CES1ACKR3L3MBTL1RAB9A | |
| SCHEMBL29669985 | 0.82 | CES2 (0.61) | CES2CES1ACKR3L3MBTL1RAB9A | |
| SCHEMBL31529633 | 0.82 | CES2 (0.61) | CES2CES1ACKR3L3MBTL1RAB9A | |
| SCHEMBL962932 | 0.82 | CES2 (0.61) | CES2CES1ACKR3L3MBTL1RAB9A | |
| SCHEMBL196379 | 0.82 | CES2 (0.61) | CES2CES1ACKR3L3MBTL1KCNH2 | |
| SCHEMBL19104747 | 0.82 | CES2 (0.61) | CES2CES1ACKR3L3MBTL1RAB9A | |
| SCHEMBL2597507 | 0.82 | CES2 (0.61) | CES2CES1ACKR3L3MBTL1RAB9A | |
| SCHEMBL31573474 | 0.80 | PKM (0.45) | CES2CES1RAB9AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116854621-A | Photosensitizer taking pentamethine cyanine dye as matrix, and synthesis method and application thereof | 大连理工大学 | 2023-10-10 | — | — | CN | disclosed |
| CN-105712945-B | 2-substituted oxy-5-methylsulfonyl aryl piperazine amide analogue and preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2020-12-01 | — | — | CN | disclosed |
| EP-3436433-B1 | DERIVATIVES OF PYRROLE-2,5-DIONES HAVING A FUNGICIDAL ACTIVITY, THEIR AGRONOMICAL COMPOSITIONS AND USE THEREOF. | ISAGRO SPA (IT) | 2020-01-22 | — | — | EP | disclosed |
| US-10464893-B2 | Derivatives of pyrrole-2,5-diones having a fungicidal activity, their agronomical compositions and use thereof | ISAGRO S.P.A (IT) | 2019-11-05 | — | — | US | disclosed |
| US-10441946-B2 | Linear alpha-olefin catalysts and preparation and use thereof | APALENE TECHNOLOGY CO., LTD. (HANGZHOU) (CN) | 2019-10-15 | — | — | US | disclosed |
| US-20190106388-A1 | DERIVATIVES OF PYRROLE-2,5-DIONES HAVING A FUNGICIDAL ACTIVITY, THEIR AGRONOMICAL COMPOSITIONS AND USE THEREOF | ISAGRO S.P.A. (IT) | 2019-04-11 | — | — | US | disclosed |
| EP-3436433-A1 | DERIVATIVES OF PYRROLE-2,5-DIONES HAVING A FUNGICIDAL ACTIVITY, THEIR AGRONOMICAL COMPOSITIONS AND USE THEREOF. | ISAGRO S.p.A. (IT) | 2019-02-06 | — | — | EP | disclosed |
| CN-105797773-B | Novel linear alhpa olefin catalyst and its preparation process and purposes | 亚培烯科技（杭州）有限公司 | 2018-11-06 | — | — | CN | disclosed |
| US-20180147571-A1 | NOVEL LINEAR ALPHA-OLEFIN CATALYSTS AND PREPARATION AND USE THEREOF | APALENE TECHNOLOGY CO., LTD. (JIAXING) (CN) | 2018-05-31 | — | — | US | disclosed |
| CN-105797774-B | Novel linear alhpa olefin catalyst and its preparation and commercial Application | 亚培烯科技(嘉兴)有限公司 | 2018-03-13 | — | — | CN | disclosed |
| US-20120183563-A1 | IMINOTHIADIAZINE DIOXIDE COMPOUNDS AS BACE INHIBITORS, COMPOSITIONS AND THEIR USE | MERCK SHARP & DOHME LLC | 2012-07-19 | — | — | US | disclosed |
| US-20110230465-A1 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGLEHEIM INTERNATIONAL GMBH (DE) | 2011-09-22 | — | — | US | disclosed |
| CN-102186921-A | Fluorine-containing copolymer composition and process for production thereof | ASAHI GLASS CO LTD | 2011-09-14 | — | — | CN | disclosed |
| WO-2011044187-A1 | IMINOTHIADIAZINE DIOXIDE COMPOUNDS AS BACE INHIBITORS, COMPOSITIONS, AND THEIR USE | SCHERING CORPORATION (US) | 2011-04-14 | — | — | WO | disclosed |
| WO-2011044181-A1 | IMINOTHIADIAZINE DIOXIDE COMPOUNDS AS BACE INHIBITORS, COMPOSITIONS, AND THEIR USE | SCHERING CORPORATION (US) | 2011-04-14 | — | — | WO | disclosed |
| US-4960782-A | Triazole antifungal agents | PFIZER INC. (US) | 1990-10-02 | — | — | US | disclosed |
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |
| EP-0118245-B1 | TRIAZOLE ANTIFUNGAL AGENTS | Pfizer Limited (GB) | 1987-05-13 | — | — | EP | disclosed |
| EP-0153803-A2 | Triazole antifungal agents | Pfizer Limited (GB) | 1985-09-04 | — | — | EP | disclosed |
| EP-0118245-A1 | Triazole antifungal agents | Pfizer Limited (GB) | 1984-09-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190106388-A1 | DERIVATIVES OF PYRROLE-2,5-DIONES HAVING A FUNGICIDAL ACTIVITY, THEIR AGRONOMICAL COMPOSITIONS AND USE THEREOF | CYP51A1, DDT, DHPS | CES2 1227/4885CES1 1394/4885ACKR3 4873/4885 |
| US-20180147571-A1 | NOVEL LINEAR ALPHA-OLEFIN CATALYSTS AND PREPARATION AND USE THEREOF | UBE2L3, RNF168, AGL | CES2 3575/4885CES1 3464/4885ACKR3 53/4885 |
| US-10464893-B2 | Derivatives of pyrrole-2,5-diones having a fungicidal activity, their agronomical compositions and use thereof | CYP51A1, DDT, DHPS | CES2 1227/4885CES1 1394/4885ACKR3 4873/4885 |
| US-20120183563-A1 | IMINOTHIADIAZINE DIOXIDE COMPOUNDS AS BACE INHIBITORS, COMPOSITIONS AND THEIR USE | BACE1, BACE2, APP | CES2 4315/4885CES1 2966/4885ACKR3 4762/4885 |
| US-10441946-B2 | Linear alpha-olefin catalysts and preparation and use thereof | UBE2L3, COG8, ACSL3 | CES2 3635/4885CES1 3277/4885ACKR3 95/4885 |
| US-20110230465-A1 | VIRAL POLYMERASE INHIBITORS | POLR2A, POLR2H, POLR2E | CES2 1076/4885CES1 269/4885ACKR3 2839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.