SCHEMBL532602

SCHEMBL532602

COC(=O)c1ccc(N2CCNCC2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.65
TSHR P16473 3/20 0.59
HSD17B10 Q99714 2/20 0.59
USP2 O75604 1/20 0.59
ADRB1 P08588 4/20 0.57
HTR3E A5X5Y0 2/20 0.57
HTR3B O95264 2/20 0.57
HTR3A P46098 2/20 0.57
HTR3D Q70Z44 2/20 0.57
HTR3C Q8WXA8 2/20 0.57
SIGMAR1 Q99720 2/20 0.57
OPRD1 P41143 1/20 0.56
MAPT P10636 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
KDR P35968 1/20 0.49
NPC1 O15118 4/20 0.49
RAB9A P51151 3/20 0.49
KMT2A Q03164 2/20 0.49
MAOB P27338 1/20 0.49
HPGD P15428 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28823824 0.98 ALDH1A1 (0.63) ALDH1A1TSHRHSD17B10USP2ADRB1
Tert-Butyl Formate SCHEMBL27908417 0.88 ALDH1A1 (0.52) ALDH1A1TSHRHSD17B10USP2ADRB1
SCHEMBL27821389 0.87 ALDH1A1 (0.54) ALDH1A1TSHRHSD17B10USP2ADRB1
Trifluoroacetic Acid SCHEMBL6132228 0.87 ALDH1A1 (0.51) ALDH1A1TSHRHSD17B10USP2ADRB1
SCHEMBL20897465 0.84 ALDH1A1 (0.71) ALDH1A1TSHRHSD17B10MAPTSMN1; SMN2
SCHEMBL2951325 0.84 ALDH1A1 (0.71) ALDH1A1TSHRHSD17B10USP2MAPT
SCHEMBL5742108 0.83 ALDH1A1 (0.69) ALDH1A1TSHRHSD17B10MAPTSMN1; SMN2
SCHEMBL62795 0.83 HPGD (0.56) ALDH1A1TSHRHSD17B10USP2ADRB1
SCHEMBL5536717 0.83 ALDH1A1 (0.55) ALDH1A1TSHRHSD17B10USP2ADRB1
Hydrochloric Acid SCHEMBL31490556 0.82 ADRB1 (0.51) ALDH1A1TSHRHSD17B10USP2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 295 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122059950-A Compounds with proteasome agonistic activity, preparation method and application thereof 浙大城市学院 2026-05-19 CN disclosed
US-20260092057-A1 BCL-XL/BCL-2 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-04-02 US disclosed
US-RE50643-E1 Benzamide compounds RECURIUM IP HOLDINGS, LLC (US) 2025-10-21 US disclosed
EP-4556469-A1 BENZAMIDE COMPOUNDS Recurium IP Holdings, LLC (US) 2025-05-21 EP disclosed
US-12269814-B2 Process for preparing a compound useful to treat mycoses PULMOCIDE LIMITED (GB) 2025-04-08 US disclosed
CN-119698414-A Indole-phenyl piperidine compound and preparation method and application thereof 深圳信立泰药业股份有限公司 2025-03-25 CN disclosed
EP-4522154-A1 BCL-XL/BCL-2 DEGRADERS AND USES THEREOF Kymera Therapeutics, Inc. (US) 2025-03-19 EP disclosed
WO-2025011623-A1 CYANOQUINOLINE-TARGETING PROTEIN DEGRADATION MOLECULE, PREPARATION METHOD THEREFOR AND USE THEREOF 上海壹迪生物技术有限公司 2025-01-16 WO disclosed
US-12195472-B2 Substituted indole Mcl-1 inhibitors VANDERBILT UNIVERSITY (US) 2025-01-14 US disclosed
EP-3740487-B1 BENZAMIDE COMPOUNDS AS BCI INHIBITORS FOR THE TREATMENT OF HIV RECURIUM IP HOLDINGS LLC (US) 2025-01-08 EP disclosed
US-5854245-A Fibrinogen receptor antagonists MERCK & CO., INC. (US) 1998-12-29 US disclosed
WO-1998041527-A1 PYRROLOAZEPINE COMPOUNDS SUNTORY LIMITED (JP) 1998-09-24 WO disclosed
WO-1998000144-A1 FIBRINOGEN RECEPTOR ANTAGONIST PRODRUGS MERCK & CO., INC. (US) 1998-01-08 WO disclosed
WO-1998000401-A1 FIBRINOGEN RECEPTOR ANTAGONIST PRODRUGS MERCK & CO., INC. (US) 1998-01-08 WO disclosed
EP-0807632-A1 PYRROLOAZEPINE DERIVATIVES SUNTORY LIMITED (JP) 1997-11-19 EP disclosed
EP-0749967-A1 Substituted benzothiazine derivative SUNTORY LIMITED (JP) 1996-12-27 EP disclosed
EP-0749971-A1 Thiopyran derivatives SUNTORY LIMITED (JP) 1996-12-27 EP disclosed
CN-1119859-A benzothiazine derivatives SUNTORY LTD (JP) 1996-04-03 CN disclosed
EP-0686632-A1 BENZOTHIAZINE DERIVATIVE SUNTORY LIMITED (JP) 1995-12-13 EP disclosed
WO-1995018118-A1 HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF CNS AND CARDIOVASCULAR DISORDERS THE UPJOHN COMPANY (US) 1995-07-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092057-A1 BCL-XL/BCL-2 DEGRADERS AND USES THEREOF BCL2L2, BCL2A1, BCL2L1 ALDH1A1 1304/4885TSHR 1810/4885HSD17B10 1049/4885
US-12195472-B2 Substituted indole Mcl-1 inhibitors MCL1, BCL2L1, BCL3 ALDH1A1 1900/4885TSHR 4554/4885HSD17B10 3461/4885
US-12269814-B2 Process for preparing a compound useful to treat mycoses C1R, CBR1, CBR3 ALDH1A1 3385/4885TSHR 533/4885HSD17B10 953/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.