Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3197854 | 0.74 | POLB (0.72) | MEN1KMT2ACYP1A2CYP2C9TP53 | |
| SCHEMBL5324564 | 0.72 | MAPT (0.61) | MEN1KMT2ATP53POLBMAPT | |
| SCHEMBL5323358 | 0.72 | MAPT (0.46) | MEN1KMT2ATP53POLBMAPT | |
| SCHEMBL5321302 | 0.70 | MAPT (0.39) | MEN1KMT2ACYP1A2CYP2C9TP53 | |
| SCHEMBL5326550 | 0.68 | MEN1 (0.69) | MEN1KMT2ACYP1A2CYP2C9TP53 | |
| SCHEMBL4016493 | 0.65 | CCR1 (0.39) | MEN1KMT2APOLBMAPTUSP2 | |
| SCHEMBL3188362 | 0.63 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP2C9TP53 | |
| SCHEMBL19009086 | 0.62 | MEN1 (0.53) | MEN1KMT2ATP53MAPTUSP2 | |
| SCHEMBL3185770 | 0.61 | POLB (0.74) | MEN1KMT2ACYP1A2CYP2C9TP53 | |
| SCHEMBL27974385 | 0.61 | TSHR (0.55) | MEN1KMT2ATP53POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007115232-A2 | CXCR4 MODULATORS | CHEMOCENTRYX, INC. (US) | 2007-10-11 | — | — | WO | disclosed |