Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3195671 | 0.76 | MEN1 (0.52) | MAPTMEN1CYP1A2CYP2C9KMT2A | |
| SCHEMBL9537880 | 0.73 | MAPT (0.51) | MAPTRXFP1MEN1CYP1A2CYP2C9 | |
| SCHEMBL5326087 | 0.70 | MEN1 (0.46) | MAPTMEN1CYP1A2CYP2C9KMT2A | |
| SCHEMBL3200470 | 0.64 | MAPT (0.54) | MAPTMEN1CYP1A2CYP2C9KMT2A | |
| SCHEMBL5323358 | 0.64 | MAPT (0.46) | MAPTRXFP1MEN1KMT2ATP53 | |
| SCHEMBL21574277 | 0.61 | NR1H4 (0.51) | MAPTRXFP1THRBNR1H4HTT | |
| SCHEMBL29202265 | 0.59 | MEN1 (0.45) | MAPTRXFP1MEN1CYP1A2CYP2C9 | |
| SCHEMBL5326550 | 0.58 | MEN1 (0.69) | MAPTMEN1CYP1A2CYP2C9KMT2A | |
| SCHEMBL26654657 | 0.58 | TP53 (0.43) | MAPTMEN1CYP1A2CYP2C9KMT2A | |
| SCHEMBL22049536 | 0.57 | MAOB (0.57) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007115232-A2 | CXCR4 MODULATORS | CHEMOCENTRYX, INC. (US) | 2007-10-11 | — | — | WO | disclosed |