Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | TP53 | P04637 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.34 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325470 | 0.90 | TP53 (0.55) | MAPTTP53GAAHSD17B10KDM4E | |
| SCHEMBL5324564 | 0.88 | MAPT (0.61) | MAPTTP53GAAKDM4ERXFP1 | |
| SCHEMBL5323078 | 0.81 | TP53 (0.44) | MAPTTP53GAAHSD17B10KDM4E | |
| SCHEMBL5326013 | 0.80 | KDM4E (0.58) | MAPTTP53GAAHSD17B10KDM4E | |
| SCHEMBL3189890 | 0.74 | TP53 (0.81) | MAPTTP53GAAHSD17B10KDM4E | |
| SCHEMBL5326087 | 0.72 | MEN1 (0.46) | MAPTTP53GAALMNAPOLB | |
| SCHEMBL3188884 | 0.64 | TP53 (0.82) | MAPTTP53GAAHSD17B10KDM4E | |
| SCHEMBL3198625 | 0.64 | TP53 (0.82) | MAPTTP53GAAHSD17B10KDM4E | |
| SCHEMBL5321302 | 0.64 | MAPT (0.39) | MAPTTP53KDM4ERXFP1ALDH1A1 | |
| SCHEMBL5698648 | 0.63 | SMN1; SMN2 (0.47) | MAPTKDM4ELMNAPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007115232-A2 | CXCR4 MODULATORS | CHEMOCENTRYX, INC. (US) | 2007-10-11 | — | — | WO | disclosed |