Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 5/20 | 0.38 |
| ▸ | ACHE | P22303 | 4/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | MC5R | P33032 | 1/20 | 0.36 |
| ▸ | MC3R | P41968 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5320739 | 0.94 | ALDH1A1 (0.44) | ICMTALDH1A1MAPTL3MBTL1TACR1 | |
| SCHEMBL5389491 | 0.89 | ALDH1A1 (0.44) | ALDH1A1MAPTL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL5321455 | 0.89 | ALDH1A1 (0.45) | ALDH1A1MAPTL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL5323221 | 0.89 | MAPT (0.45) | ICMTALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL5326162 | 0.88 | ALDH1A1 (0.46) | ALDH1A1MAPTL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL5326617 | 0.87 | ALDH1A1 (0.45) | ICMTALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL5329767 | 0.87 | MAPT (0.45) | ALDH1A1MAPTL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL5325121 | 0.87 | ALDH1A1 (0.45) | ALDH1A1MAPTL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL5328167 | 0.87 | MAPT (0.44) | ICMTALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL5324911 | 0.86 | ICMT (0.45) | ICMTALDH1A1MAPTL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007115231-A2 | CXCR4 MODULATORS | CHEMOCENTRYX, INC. (US) | 2007-10-11 | — | — | WO | disclosed |