Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14387062 | 0.89 | ERN1 (0.38) | ERN1ABCG2CYP1A1CYP1B1CYP1A2 | |
| SCHEMBL5328582 | 0.82 | ERN1 (0.53) | ERN1ABCG2CYP1A1CYP1B1CYP1A2 | |
| SCHEMBL5330030 | 0.74 | ERN1 (0.64) | ERN1ABCG2CYP1A1CYP1B1CYP1A2 | |
| SCHEMBL23043041 | 0.73 | DRD2 (0.46) | CYP1A1CYP1B1CYP1A2DRD2PTGS2 | |
| SCHEMBL6710989 | 0.73 | GAA (0.44) | CYP1A1CYP1B1CYP1A2DRD2PTGS2 | |
| SCHEMBL13640332 | 0.71 | CA12 (0.59) | CYP1A1CYP1B1CYP1A2LMNADRD2 | |
| SCHEMBL2912460 | 0.69 | ALDH1A1 (0.50) | CYP1A1CYP1B1CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL25665189 | 0.69 | ALDH1A1 (0.42) | ERN1CYP1A2LMNADRD2KDM4E | |
| SCHEMBL21275477 | 0.69 | ERN1 (0.51) | ERN1ABCG2CYP1A1CYP1B1CYP1A2 | |
| SCHEMBL27090471 | 0.68 | LMNA (0.42) | ERN1ABCG2CYP1A1CYP1B1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007134421-A1 | 2-VINYL INDOLES, PYRIDO AND AZEPINO INDOLE DERIVATIVES, 2-ALKYNYL INDOLES, 2-ALKYNYL BENZO[b]FURANS, THEIR PRECURSORS AND NOVEL PROCESSES FOR THE PREPARATION THEREOF | LAUTENS MARK (CA) | 2007-11-29 | — | — | WO | disclosed |