Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | GUSB | P08236 | 1/20 | 0.67 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19752674 | 1.00 | USP2 (0.71) | USP2TDP1PKMGUSBADORA2B | |
| SCHEMBL10279640 | 0.88 | PKM (0.67) | PKMGUSBADORA2BKMT2AKDM4E | |
| SCHEMBL10112947 | 0.87 | HSD17B10 (0.69) | PKMGUSBADORA2BKMT2AKDM4E | |
| SCHEMBL5347891 | 0.86 | KIF11 (0.75) | ADORA2BPOLBHSD17B10TSHR | |
| SCHEMBL19752667 | 0.86 | KIF11 (0.75) | ADORA2BPOLBHSD17B10TSHR | |
| SCHEMBL18025267 | 0.86 | KIF11 (0.75) | ADORA2BPOLBHSD17B10TSHR | |
| SCHEMBL28595517 | 0.86 | ALDH1A1 (0.78) | PKMGUSBKMT2AKDM4EMEN1 | |
| SCHEMBL19732955 | 0.84 | USP2 (0.79) | USP2TDP1KMT2APOLBKDM4E | |
| SCHEMBL13789190 | 0.84 | USP2 (0.79) | USP2TDP1KMT2APOLBKDM4E | |
| SCHEMBL19732923 | 0.84 | USP2 (0.79) | USP2TDP1KMT2APOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110437100-B | Preparation method and application of novel ionic salicylaldehyde Schiff base zirconium complex | 山西医科大学 | 2022-03-11 | — | — | CN | disclosed |
| WO-2007105233-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF 4,5,6-SUBSTITUTED 3,4-DIHYDROPYRIMIDIN-2-ONES AND THEIR 2-THIOXO ANALOGUES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2007-09-20 | — | — | WO | disclosed |
| US-5786472-A | CATALYTIC CONDENSATION OF UREA WITH DIKETONES USIN BORON REAGENT AND ACID CATALYST | MERCK & CO., INC. (US) | 1998-07-28 | — | — | US | disclosed |